You can paste any image previously copied to the system wide clipboard into xyscan using the Edit->Paste Image menu command.
This is an especially powerful feature that allows you to grab plots from PDF documents, Power Point, Keynote, OpenOffice, and many other applications and paste them directly into xyscan. In Acrobat Reader use the snapshot tool to copy an rectangle to the clipboard. Remember that the plot will appear in xyscan in exactly the same size as you see it in the Acrobat Reader. Zoom in it first and enlarge it to a reasonable size. The larger the plot the more precise the scan will be. Although you can increase the size of the plot once loaded using the Plot Adjustments dialog (see Rotating and Scaling Plots) this typically will not increase the precision.